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A wakefulness-promoting agent, or eugeroic, is a type of drug which specifically improves wakefulness and alertness.〔〔 They are used mainly in the treatment of sleeping disorders, excessive daytime sleepiness and narcolepsy.〔〔 They are also used merely to counteract fatigue and lethargy and to enhance motivation and productivity. Wakefulness-promoting agents are addictive,〔〔 although not necessarily to the same extent as other addictive stimulants. The prototypical eugeroic is modafinil, and other drugs include adrafinil and armodafinil. Modafinil and armodafinil are dopamine reuptake inhibitors. The functional opposites of wakefulness-promoting agents are hypnotics, such as H1 antihistamines that cross the blood–brain barrier and suvorexant, an orexin antagonist. ==Examples== * Adrafinil (Olmifon) * Armodafinil (Nuvigil) * CRL-40,941 (fladrafinil or fluorafinil) * CRL-40,940 (Flmodafinil, Flodafinil or Fluoromodafinil) * Modafinil (Provigil, Alertec) * Fluorenol (Hydrafinil) ==Wakefulness Reducing Agent== The only functional opposite of wakefulness enhancing agents. * Suvorexant (Belsomra) 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Wakefulness-promoting agent」の詳細全文を読む スポンサード リンク
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